In suspected anaphylaxis, which of the following is a respiratory sign?

• A. Throat tightness
• B. Shortness of breath
• C. Wheezing
• D. Nausea

Answer: (A)

Airway involvement is a defining feature of suspected anaphylaxis, and recognizing signs that indicate airway compromise is crucial. Throat tightness directly reflects swelling and constriction of the airway, signaling a respiratory problem at the level of the throat and upper airway. That direct link to airway edema makes it a clearer respiratory sign in this context than other options. Shortness of breath can be a subjective feeling reported by the patient and may occur for various reasons, while wheezing indicates bronchospasm but is a less direct marker of airway edema. Nausea is not related to respiration. So throat tightness stands out as the clear respiratory sign signaling airway involvement in anaphylaxis.