BRUE stands for and four signs?

• A. Brief, Resolved, Unexplained Event; Absent, decreased, or irregular breathing; Color change (cyanosis or pallor); Marked change in muscle tone (hypertonia or hypotonia); Altered level of responsiveness
• B. Brief, Resolved, Unexplained Event; Normal breathing; No color change; Normal muscle tone; Normal responsiveness
• C. Brief, Rapid, Unexplained Event; Absent breathing; Color change; Hypertonia; Altered responsiveness
• D. Brief, Regulated, Unexplained Event; Irregular breathing; Color change; Altered tone; Altered responsiveness

Answer: (A)

BRUE means a brief, resolved, unexplained event in an infant younger than 1 year that is witnessed by a caregiver and characterized by one or more of four signs: absent, decreased, or irregular breathing; color change (cyanosis or pallor); a marked change in muscle tone (hypertonia or hypotonia); and an altered level of responsiveness. This combination is the best answer because it matches the official definition and lists the four specific signs that define BRUE. The event is brief, the infant returns to baseline (resolved), and no cause is found after initial evaluation (unexplained).

Other options fail because they either change the acronym (using Rapid or Regulated instead of Resolved) or describe normal findings (normal breathing, color, tone, and responsiveness) or omit one of the key signs, which would not fit the BRUE criteria.